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GPR183 antagonist-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162011
    GPR183 antagonist-2

    		EBI2/GPR183 Inflammation/Immunology
    GPR183 antagonist-2 (compound 32) is a selective GPR183 antagonist with good water solubility and excellent pharmacokinetic properties. GPR183 antagonist-2 significantly reduces paw and joint swelling and gene expression of pro-inflammatory cytokines (MCP-1, MMPs, and VEGF) in a collagen-induced arthritis (CIA) mouse model in a dose-dependent manner. GPR183 antagonist-2 can be used in the study of autoimmune diseases .
    <em>GPR183</em> <em>antagonist-2</em>

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